The threat of avian influenza a (H5N1): part II: Clues to pathogenicity and pathology
Identifieur interne : 003869 ( Main/Exploration ); précédent : 003868; suivant : 003870The threat of avian influenza a (H5N1): part II: Clues to pathogenicity and pathology
Auteurs : Jindrich Cinatl Jr [Allemagne] ; Martin Michaelis [Allemagne] ; Hans W. Doerr [Allemagne]Source :
- Medical Microbiology and Immunology [ 0300-8584 ] ; 2007-12-01.
Abstract
Abstract: Among emerging and re-emerging infectious diseases, influenza constitutes one of the major threats to mankind. In this review series epidemiologic, virologic and pathologic concerns raised by infections of humans with avian influenza virus A/H5N1 are discussed. The second part focuses on experimental and clinical results, which give insights in the pathogenic mechanisms of H5N1 infection in humans. H5N1 is poorly transmitted to humans. However, H5N1-induced disease is very severe. More information on the role entry barriers, H5N1 target cells and on H5N1-induced modulation of the host immune response is needed to learn more about the determinants of H5N1 pathogenicity.
Url:
DOI: 10.1007/s00430-007-0045-2
Affiliations:
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In this review series epidemiologic, virologic and pathologic concerns raised by infections of humans with avian influenza virus A/H5N1 are discussed. The second part focuses on experimental and clinical results, which give insights in the pathogenic mechanisms of H5N1 infection in humans. H5N1 is poorly transmitted to humans. However, H5N1-induced disease is very severe. More information on the role entry barriers, H5N1 target cells and on H5N1-induced modulation of the host immune response is needed to learn more about the determinants of H5N1 pathogenicity.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>District de Darmstadt</li><li>Hesse (Land)</li></region><settlement><li>Francfort-sur-le-Main</li></settlement></list><tree><country name="Allemagne"><region name="Hesse (Land)"><name sortKey="Cinatl Jr, Jindrich" sort="Cinatl Jr, Jindrich" uniqKey="Cinatl Jr J" first="Jindrich" last="Cinatl Jr">Jindrich Cinatl Jr</name></region><name sortKey="Cinatl Jr, Jindrich" sort="Cinatl Jr, Jindrich" uniqKey="Cinatl Jr J" first="Jindrich" last="Cinatl Jr">Jindrich Cinatl Jr</name><name sortKey="Doerr, Hans W" sort="Doerr, Hans W" uniqKey="Doerr H" first="Hans W." last="Doerr">Hans W. Doerr</name><name sortKey="Doerr, Hans W" sort="Doerr, Hans W" uniqKey="Doerr H" first="Hans W." last="Doerr">Hans W. Doerr</name><name sortKey="Michaelis, Martin" sort="Michaelis, Martin" uniqKey="Michaelis M" first="Martin" last="Michaelis">Martin Michaelis</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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